• What are the attitudes of people in the general population toward predictive risk estimation for Alzheimer's dementia?
• What impact does predictive testing have on individuals and their families?
• What factors influence the use of predictive testing?
• What are the obligations for legally sound information, education, and consent for predictive testing?
• What are the implications of increasingly easy access to individual risk estimation for society, public discourse, the law, and the health care system?
• How is language used to deal with the increasing possibilities of predictive testing?

In the PreTAD project, individual needs and different perspectives regarding the prediction of Alzheimer's dementia will be elaborated. To this end, this study will interview individuals with subjective symptoms of memory impairment (SCD, subjective cognitive decline), individuals with a family history of AD or APOE4 allele carriers, and healthy individuals.
The aim of the project is to explore the implications of the paradigm shift towards predictive medicine, using Alzheimer's dementia as an example on an individual, linguistic, legal and societal level in order to derive implications for practice. Recommendations for an ethically and legally appropriate handling of the possibilities of predictive medicine for the field of Alzheimer's dementia will be developed.